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drug-medicine : amiloride

 

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Medicine: amiloride 

INFORMATION FOR PATIENTS

AMILORIDE 5MG TABLETS BP

Read all of this leaflet carefully before you start taking this medicine.

If you have further questions, please ask your doctor or your pharmacist.

This medicine has been prescribed for you personally and you should not pass it on to others. It may harm them, even if their symptoms are the same as yours.

In this leaflet:

  • 1. What amiloride is and what it is used for
  • 2. Before you take amiloride
  • 3. How to take amiloride
  • 4. Possible side effects
  • 5. Storing amiloride tablets

AMILORIDE 5MG TABLETS BP

The active substance is amiloride hydrochloride (anhydrous equivalent) 5.0mg.

The other ingredients are lactose monohydrate, starch, povidone, sodium starch glycollate, magnesium stearate, dispersed quinoline yellow lake E104 and isopropanol

1. WHAT AMILORIDE IS AND WHAT IT IS USED FOR

Amiloride belongs to the class of drugs known as potassium-sparing diuretics (water tablets) which increase urine production, but conserve potassium.

Amiloride is used either alone or in combination with other diuretics (water tablets) to treat fluid retention (oedema) and high blood pressure.

2. BEFORE YOU TAKE AMILORIDE TABLETS

If you have any doubts about whether you should take these tablets then discuss things fully with your doctor BEFORE taking them.

Do not take amiloride if:-

  • You have been told that you are sensitive to amiloride or any other ingredients in this tablet. Check by reading the ingredients above.
  • You have been told you have high levels of potassium in your blood (hyperkalaemia) or are taking other potassium conserving drugs or potassium supplements.
  • You have diabetes, kidney or liver problems.
  • You are under 18 years of age.

Take special care with amiloride:

If your doctor tells you that you need a glucose tolerance test, you should stop taking amiloride for at least three days before the test. Your doctor will advise you.

If you are elderly or seriously ill you may be more sensitive to the effects of amiloride.

Pregnancy

Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or wish to become pregnant.

Breast-feeding

Ask you doctor or pharmacist for advice before taking any medicine if you start breast-feeding whist taking this medicine.

Driving and using machines:

If you feel dizzy while taking amiloride tablets don't drive or operate dangerous machinery.

Drinking alcohol:

If you feel dizzy while taking the tablets drinking alcohol can make this problem worse.

 

Taking other medicines:

Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed.

There may be some problems when amiloride tablets are taken with other medicines, including:

Medicines used for lowering high blood pressure, including ACE inhibitors, beta-blockers, alpha-blockers, calcium channel blockers and angiotensin-II antagonists.

Non-steroidal anti-inflammatory drugs (such as aspirin, ibuprofen, diclofenac and indometacin)

Trilostane, used to treat adrenal gland problems

Some oral contraceptives (the pill) or oestrogen (female sex hormone) preparations

Chlorpropamide, a drug used to treat diabetes

Medicines used to treat depression including tricyclic antidepressants, such as amitriptyline and monoamine oxidase inhibitors (MAOIs) such as phenelzine.

Alprostadil, used to treat male impotence and for heart defects in infants

Carbamazepine, used to treat epilepsy

Carbenoxolone, used to treat stomach ulcers

Ciclosporin and tacrolimus, used to prevent organ rejection in transplantation

Lithium, used to treat mental problems

Quinidine, used to treat disorders of heart rhythm.

Steroids, used to suppress inflammation and allergy.

Terfenadine, used to treat hayfever and other allergies.

Tizanidine, used to relax muscles

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3. HOW TO TAKE AMILORIDE TABLETS

The usual dose of amiloride in adults is 5mg to 10mg once or twice daily. Your doctor may decide to increase the dose up to a maximum of four tablets daily. If used with other diuretics (water tablets) the usual dose is 5mg or 10 mg daily.

If you are elderly you may be given a different dose which will be decided by your doctor.

If you have the impression that the effect of amiloride is too strong or too weak, talk to your doctor or pharmacist.

Your doctor will decide which dose is best for you. Always follow your doctor's instructions completely and also follow any special instructions or warnings that appear on the label that the pharmacist has put on the package. If you do not understand, or are in any doubt, ask your doctor or pharmacist.

To obtain a tablet, press on the tablet from the blister (or bubble) side, pushing it through the foil. Do not remove the tablet from the blister until you are ready to take it.

Do not stop taking amiloride tablets unless your doctor tells you to.

If you take more amiloride tablets than you should you may feel dehydrated (very thirsty).
Contact your doctor, pharmacist or hospital as soon as possible.
Take this leaflet and any tablets you have left to show your doctor or pharmacist

If you forget to take your amiloride tablets:

Take another as soon as you remember. If it is almost time for your next dose then do not take the missed dose at all.

Never double the next dose to make up for the one missed.

 

4. POSSIBLE SIDE EFFECTS

Like all medicines, amiloride can have side-effects in some patients, particularly when treatment is first started. These include feeling sick, being sick, constipation or diarrhoea, stomach pain, headache, dizziness (particularly on standing up), muscle cramps, dry mouth, thirst, weakness, feeling sleepy or confusion. Changes in blood composition may occur, especially high blood potassium.
Other side-effects include rash, itching, pins and needles, mood or personality changes, reduced sexual desire, liver problems, including jaundice (skin or whites of the eyes turn yellow) in patients who already have liver disease. Rarely, blood disorders have been reported.
If you notice any side effects not mentioned in this leaflet or feel that the medicine is affecting you badly, please inform your doctor or pharmacist.

 

5. STORING AMILORIDE TABLETS

Keep out of the reach and sight of children

Store in the original package container. Do not transfer them to another container.

Keep the container in the outer carton

Do not use after the expiry date stated on the label.

Do not take your amiloride tablets if you notice that they show signs of deterioration such as discoloration.

REMEMBER this medicine has been prescribed for you. DO NOT give it to anyone else as it may harm them, even if their symptoms are the same as yours.

Unless your doctor tells you to, do not keep tablets that you no longer need. Give them back to your pharmacist.

 

Medicamentweb.com, the website for Patient Information Leaflets, is dedicated to share information about pharmaceutical products with the general public, and is particularly interested in making PILs available online. Of course, this information cannot replace the advice of your GP, doctor or pharmacist. If you should be worried in any way about your health, we urge you to see a doctor.

 

 

 

 

 

 

 

 

 

 

 

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