INFORMATION FOR PATIENTS

Please read this leaflet carefully before you start to take this medicine. It gives an outline of the more important things you should know. If you want to know more about this medicine, or you are not sure about anything, ask your doctor or pharmacist. You should keep this leaflet throughout your course of treatment.

THE NAME OF YOUR MEDICINE IS DOMPERIDONE TABLETS 10MG

Domperidone Tablets contain the active ingredient domperidone maleate.

Domperidone tablets 10mg are white, circular, film coated tablets marked DM on one face, 10 on the reverse and contain 10mg domperidone, as domperidone maleate.

Other ingredients in your tablets are lactose, pregelatinised maize starch, microcrystalline cellulose, sodium starch glycollate, magnesium stearate and Opadry white OY-S-28899 which consists of hypromellose, titanium dioxide (E171) and macrogol.

Domperidone tablets 10mg are available in strip packs of 30 or 100 tablets.

HOW DOES YOUR MEDICINE WORK?

Domperidone belongs to a group of medicines called antiemetics. These medicines work by acting on your digestive system, helping to suppress nausea (feeling sick) and vomiting (being sick).

WHAT ARE DOMPERIDONE TABLETS FOR?

Domperidone tablets are used to treat nausea and vomiting, indigestion or a feeling of discomfort or fullness in the stomach.

 

BEFORE TAKING THIS MEDICINE

You should not take domperidone tablets if:

• You have ever had a reaction to or been told that you are allergic to domperidone or any of the other ingredients in the tablets. Check by reading the list of ingredients above.
• You are a child weighing less than 35kg
• You have bleeding from the stomach or intestines, a blockage in the intestines, a perforated ulcer.
• You have a tumour on the pituitary gland called a prolactinoma.
• You have liver problems
• You are breastfeeding

Before taking this medicine, you should let your doctor know if you are pregnant or are planning to become pregnant.

Taking another medicine while you are taking domperidone can affect how it or the other medicine works. Make sure that your doctor knows what other medicines you are taking. Do not take any other medicines while you are taking domperidone unless you have told your doctor or pharmacist and asked their advice. This includes medicines you may have bought yourself.

Examples of medicines that can affect domperidone are:

• ketonazole, used to treat fungal infections
• ritonavir, used to treat virus infections
• erythromycin, used to treat bacterial infections

If you have any doubts about whether you should take this medicine then talk to your doctor.

TAKING THIS MEDICINE

The usual dose for nausea and vomiting in adults is 10-20mg (1-2 tablets) three to four times a day.

You should not take the tablets for more than four weeks without consulting your doctor.

The dose should be reduced for patients with severe kidney problems and reviewed regularly by your doctor.

The usual dose for children is 250 - 500 micrograms/kg three to four times a day, maximum 8 tablets per day.

Your doctor will decide the dose that is best for you. Always follow your doctor's instructions completely. Also, follow any instructions or warnings that appear on the label that the pharmacist has put on the pack. If you do not understand, or are in any doubt, ask your doctor or pharmacist.

To obtain a tablet, press on the tablet from the blister (or bubble) side, pushing it through the foil. Do not remove the tablet from the blister until you are ready to take it.

Unless told otherwise, take your tablets with a glass of water.

You should take this medicine for as long as your doctor tells you to. If you forget to take a dose, take another as soon as you remember. If it is almost time for your next dose, then do not take the missed dose at all. Never double the next dose to make up for the one missed. Do not stop taking the medicine without talking to your doctor first.

If you accidentally take too many tablets you should contact your doctor, pharmacist or nearest hospital casualty department immediately. Take this leaflet and any tablets you have left to show the doctor or pharmacist.

ARE THERE ANY SIDE-EFFECTS?

Like many medicines, domperidone may cause side-effects in some patients, particularly when you first start taking them. The side-effects that some patients have had with domperidone include stomach cramps, uncontrollable movement of the face and limbs, temporary stopping of periods, secretion of milk from the breasts and breast enlargement (also in men). Occasionally rashes and other allergic reactions have been reported.

If you experience these or any other side-effects or feel that the medicine is affecting you badly, tell your doctor or pharmacist.