PATIENT
LEAFLET
ISOVISTŪ (iotrolan)
A
guide to Isovist
This
leaflet gives you some information about Isovist.
The radiographer (specially trained X-ray staff)
will explain how everything works and in what
position you should lie on the X-ray table. You will
then be given the Isovist.
X-rays,
like radio waves, can pass through objects and can
be focused to make a picture. When you have an
X-ray, the beam of rays goes through your body where
it is absorbed to differing degrees by different
tissues, such as bones, muscles and organs. When the
rays come out on the other side, they make a pattern
of light and shade on a film. Isovist helps to make
this pattern clearer. The film is then examined by a
specialist who will make a diagnosis. If you have
any questions or are not sure about anything, ask a
member of staff from the X-ray department.
The name
of this diagnostic aid is: Isovist (iotrolan)
What
does Isovist contain?
Isovist
contains iotrolan in a water-based solution for
injection.
1ml Isovist
240 contains 0.513g of iotrolan.
Isovist 240
is supplied in: Packs of 10x10ml bottles.
Isovist 240
also contains the inactive ingredients:
calcium
disodium edetate (additive number 385)
sodium bicarbonate (additive number 500)
sodium chloride
water for injections
Isovist is
an injectable contrast medium (a dye) which contains
iodine. It is used to show clearly the area your doctor
wants to investigate.
Uses
To create an
artificial contrast and clearly show the area of the
spine, brain, joints, womb, breast, bile ducts and
pancreas which your doctor wants to investigate.
Reasons for not receiving Isovist
You
should not be given Isovist if you have either of
the following:
-
Uncontrolled thyrotoxicosis (condition caused by
too much thyroid hormone).
-
You must not have the uterus (womb) investigated
with Isovist if you are pregnant or have
inflammation of the pelvic cavity.
What you
should know before you are given Isovist
If you are
epileptic or have seizures you must tell the X-ray
department.
If you are
taking antidepressants or neuroleptics (drugs which
treat mental disorders) you should talk to your doctor
who may advise you to stop taking these 48 hours before
the examination.
You should
tell the X-ray department staff about any other medicine
you are taking, in particular beta-blockers (drugs used
to treat heart or blood pressure problems) or if you
have been treated with a drug called interleukin.
Alcoholics
or drug addicts may be more likely to have an epileptic
fit.
If you
suffer from hyperthyroidism (overactive thyroid gland)
this may be made worse.
If you are
going to have an iodine test for thyroid disease,
Isovist may affect the results for 2 weeks or more after
being given it.
If you have
had an adverse reaction with any contrast medium or
think you are allergic to iodine-containing contrast
media you must tell the X-ray department.
If you have
had any allergy in the past, tell the X-ray department.
If you are
pregnant, tell the X-ray department.
If you have
reduced kidney function you must tell the X-ray
department.
How you
will be given Isovist.
The dose of
Isovist and how it will be given depends on the
investigation. The dose range is between 1 and 30 ml.
The X-ray department will decide how much Isovist is
needed for your particular investigation. Isovist will
be given immediately before the X-rays are taken.
You may be
asked not to eat anything before your examination. The
X-ray department should make sure you have had enough to
drink and that imbalances in your body salts are
corrected.
- If
you are having an investigation of your spine or
brain, you will lie down and a small amount of fluid
will first be taken out of the area to be
investigated. This is to make room for the Isovist
that will then be injected. It is then important
that you remain as still as possible. After the
investigation you will stay in bed for at least 1
hour with the head of your bed tilted up slightly.
- If
you are having an investigation of your joints, womb
or breast, Isovist will be given directly into the
area to be looked at.
- If
you are having an investigation of your bile ducts
and pancreas, Isovist will be given via a tube which
is passed down the gullet through the stomach and
into the small bowel.
Overdosage
Overdosing is unlikely. If it does happen the
specialist will treat any symptoms that follow.
Side
effects
Severe side
effects are extremely rare.
You may
experience headache, nausea, vomiting, pain or an
increase in existing pain in the back, nape of the neck
or hands and feet.
Other
symptoms which you may get are:
Hypersensitivity (allergic-type) reactions, severe
headache lasting several days may rarely happen.
After spinal
injection of contrast media, like Isovist, headache with
fever or stiff neck may occur. These symptoms usually
disappear within one week but you should tell your
doctor.
You may feel
slight muscle tension or pins and needles 2 to 6 hours
after being given Isovist, but this is rare.
Convulsions
(epileptic-like fits) may also occur. Rarely, the
following short-term side-effects have been reported:
loss of memory, confusion, hallucinations and delusions.
Delayed side
effects may occasionally happen after being given
contrast media, including Isovist. The most common
delayed side effects are itching and rashes. If they
occur you should tell your doctor.
You should
tell the X-ray staff about any changes in your health or
general sense of well-being that you notice while
Isovist is being given, or after the administration of
Isovist.
Expiry
date:
The expiry
date is printed on the label. The contrast medium should
not be used after this date.
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