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drug-medicine : kenalog intra-articular/intramuscular injection

 

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Medicine: kenalog intra-articular/intramuscular injection

 

PATIENT INFORMATION LEAFLET

KENALOG

INTRA-ARTICULAR/INTRAMUSCULAR INJECTION 40 mg/ml

Triamcinolone Acetonide

Your doctor has prescribed Kenalog injection for you. This leaflet gives a summary of information about your medicine. If you want to know more, or are not sure about anything, ask your doctor or pharmacist.

REMEMBER: This medicine is for YOU. Only a doctor can prescribe it. Never give it to anyone else. It may harm them even if they have the same symptoms as you.

WHAT IS IN KENALOG INTRA-ARTICULAR/INTRAMUSCULAR INJECTION?

Kenalog injection contains triamcinolone acetonide which is a member of the group of medicines known as steroids. The injection contains triamcinolone acetonide 40mg/ml and is supplied in 1.0ml or 2.0ml ready-filled syringes and in the U.K., also in 1.0ml glass vials.

The 1ml containers each contain 40mg triamcinolone acetonide and the 2ml syringe contains 80mg triamcinolone acetonide.

The injection can be given as an intra-articular or intramuscular injection but the needle provided with the ready-filled syringes is only for deep intramuscular injection into the large muscle of the buttock.

The other ingredients are benzyl alcohol, polysorbate 80, carmellose sodium, sodium chloride and water.

WHAT IS THIS MEDICINE FOR?

Kenalog injection is for the treatment of various inflammatory and/or allergic disorders. These include asthma, seasonal allergies, arthritis, blood disorders, hormone problems, rheumatic fever, problems with kidneys, lungs or skin.

BEFORE RECEIVING YOUR MEDICINE

Should I be receiving Kenalog Injection?

You should not receive this medicine if you have ever had an allergic reaction to similar medicines or to any of the medicines or to any of the ingredients in Kenalog injection. You should not receive this medicine if you are suffering from an infection unless your doctor has also prescribed a treatment for the infection.

Is there anything else I should discuss with my doctor before receiving Kenalog injection?

Check with your doctor before receiving Kenalog injection if you have had any recent infection, tuberculosis (TB), bowel disorders, an ulcer, blood clots, cancer, thin (brittle) bones, high blood pressure or heart failure, mental disorders, epilepsy, myasthenia gravis or glaucoma (increased pressure in your eyes).

If you are receiving long-term intramuscular treatment with Kenalog injection your doctor may advise you to eat more protein. This should help to reduce the gradual loss of weight that can sometimes occur with long-term treatment.

What if I am in contact with someone who has an infectious disease such as Chickenpox, Shingles or Measles?

Steroid medicines suppress your body's natural immune response. Therefore, if you come into contact with anyone who has an infectious disease such as chickenpox, shingles or measles, consult your doctor promptly.

Can I be immunised (vaccinated)?

While you are being treated with this medicine (or you have recently stopped a course of treatment) do not have any immunisation without consulting your doctor.

What if I am pregnant or think I may be pregnant? What if I am planning to become pregnant? What if I am breast-feeding?

You should make sure you discuss this with your doctor as soon as possible before receiving Kenalog injection.

What if I have had problems with my kidneys, liver or thyroid?

Remind your doctor as the dose of Kenalog may need to be adjusted.

Can I take other medicines?

Corticosteroids can increase the chance of bleeding from the gut caused by aspirin, ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs). If you have hypothrombinaemia (a tendency to bleed), your doctor will be more careful about giving you Kenalog if you are taking ibuprofen or another NSAID. Always tell your doctor about all other medicines you are taking, even those you have bought at a pharmacy or other places, e.g. supermarket.

Some medicines used to treat epilepsy, tuberculosis or breast cancer can reduce the effectiveness of Kenalog. On the other hand, Kenalog can affect the action of some medicines used to treat diabetes, high blood pressure, to slow the heart or to thin the blood.

Always tell your doctor if you are taking oral contraceptives, hormone replacement therapy (HRT), growth hormone, thyroid drugs, cyclosporin, medicines for treating fungal infections or if you are to be vaccinated or to be given an anaesthetic.

Is it all right to take exercise?

You must take care not to over-use a joint which feels better after you receive Kenalog injection as the joint will still need to recover from the inflammation which caused your symptoms.

Is it all right to drive?

This medicine does not usually affect your ability to drive but it can affect your eyesight. Tell your doctor immediately if you have any pain in the eyes or visual disturbances.

Is it all right to drink alcohol?

There is no known interaction between Kenalog and alcohol.

What if I am diabetic?

Remind your doctor as your insulin dose may need to be changed.

Who should I tell that I have received this injection?

Your doctor or pharmacist will have given you a Steroid Treatment Card with your prescription or medicine. YOU SHOULD ALWAYS CARRY THIS CARD WITH YOU as it must be shown to any of the following persons:

  • Doctor or Nurse - before having any surgery or emergency treatment or if any new treatment is prescribed.
  • Dentist - before having any dental surgery
  • Pharmacist - before buying any medicines
  • Optician - it is advisable to have regular eye tests.

Is there any important information about the ingredients of Kenalog that I need to know?

Kenalog injection contains 15mg/ml benzyl alcohol which may cause harmful or allergic reactions in infants and children. Kenalog injection must not be given to premature or newly born babies.

ADMINISTRATION OF YOUR MEDICINE

How will Kenalog injection be given and how often?

The effect of the injection will vary from patient to patient and further injections may be given when symptoms return and not at regular intervals.

Use in inflammatory joint disorders:

The dose of injection into a joint or into a tendon sheath depends upon the size of the joint and the condition which is being treated. Doses of 5-10mg (0.125-0.25ml) for smaller joints and up to 40mg (1.0ml) for larger joints may be given. This medicine should not be used for injection into the Achilles tendon.

 

Use in allergic disorders:

Deep intramuscular injection must be given into the large muscles of the buttock and not into the upper arm or the thigh. This medicine should not be given into a vein.

The usual starting dose is 40mg (1.0ml) injected deeply into the upper outer area of the buttock. If you require a further injection, this should be made into the same area on the other buttock. Some patients with hay fever or pollen asthma find that one injection of 40-100mg lasts throughout the pollen season.

Children: Kenalog is not recommended for children under 6 years of age. It may be given to older children but the dose is adjusted according to their size and weight and is always kept as low as possible for the shortest possible time.

During times of illness or stress, patients on long-term treatment may require the addition of oral steroid tablets, or, if they have recently finished a course of Kenalog injections, may need to start taking oral steroid tablets for a while.

How long should I continue receiving Kenalog injection?

Your doctor will advise you whether it is wise for you to have further injections. Treatment with steroids is usually kept as short as possible and must not be stopped abruptly. Joints may become permanently damaged by repeated injections over a long period of time.

When the treatment is stopped you may notice flu-like symptoms, runny nose or itchy eyes or skin.

UNDESIRABLE EFFECTS

Are there any unwanted effects of Kenalog injection?

All medicines may cause some unwanted or "side" effects. Some which can occur with steroid treatment are as follows. Tell your doctor immediately if you get ulcer pains in your stomach, severe pain in your abdomen or tarry black stools, facial swelling or an unexpected rash.

Steroid treatment may cause: Increased appetite, weight gain, indigestion, bloating, feeling tired or weak.

Increased risk of infection;

Thinning of bones or tendons causing fractures or torn muscles and muscle wasting;

Wounds or broken bones may be slow to heal;

Water retention, changes in potassium, sodium and calcium levels, heart problems, irregular heart beat, high blood pressure or blood clots, increase in white blood cells;

Skin disorders, including bruising, rashes, redness, itching, itchy raised lumps (hives) and other serious skin conditions. Acne, increased hair growth, increased sweating, flushing and thinning of the skin, and eye problems, including glaucoma and cataracts, may occur.

Treatment with steroids can stop the body from producing some hormones and may slow or stop children's growth rate.

If you are female, your periods may stop or become irregular.

Elevation or depression of mood, feelings of dependence on the medicine, worsening of psychiatric conditions, sleeplessness, dizziness, fainting, convulsions, tingling, numbness, wheezing, breathing problems and severe headaches have been reported.

When Kenalog is injected into a joint you may notice some indentation or skin discolouration appearing after a while in the surrounding area. There may also be some temporary worsening of the pain, irritation and discomfort after the injection. These changes should disappear in time.

Occasionally, Kenalog given by deep intramuscular injection produces dimpling of the buttock, caused by loss of fat under the skin. Severe pain and changes in skin colour around the injection site can also occur.

Tell your doctor or pharmacist if you notice any other troublesome side effects.

LOOKING AFTER YOUR MEDICINE

Kenalog injection will be kept in the pharmacy until it is given to you by your doctor or nurse. It should not be stored above 25°C nor should it be allowed to freeze. The container should be kept in the outer carton and this should be kept out of the reach and sight of children. It should not be used after the expiry date shown on the outer packaging.

 

Medicamentweb.com, the website for Patient Information Leaflets, is dedicated to share information about pharmaceutical products with the general public, and is particularly interested in making PILs available online. Of course, this information cannot replace the advice of your GP, doctor or pharmacist. If you should be worried in any way about your health, we urge you to see a doctor.

 

 

 

 

 

 

 

 

 

 

 

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